The Gout Studies will include about 150 patients between the ages of 21 and 80 who have a history of symptomatic Gout. The study will be conducted at study sites across the USA. All study-related care will be provided by specialty physicians and a dedicated study team.

If you qualify for a study, you will make visits to a study clinic in your area for treatment for about a month.

The Gout Studies will be evaluating the effectiveness of an investigational study drug in treating the symptoms of Gout. Volunteers who qualify to take part in the study may receive compensation for time and travel expenses.

  • 1
    If you are between the ages 21 and 80 experience gout attacks.
  • 2
    All study-related care is provided at no cost. You do not need health insurance to participate.
  • 3
    Volunteers who take part in the study may be eligible to receive compensation for their time and travel.
  • 4
    Participants will receive all study-related care from a team of medical professionals at no cost. The study will require routine visits to a research center in your area.

Who can take part in the Gout Studies?

You may be eligible to take part in the Gout Studies if you:

  • 1
    Have a history of symptomatic Gout defined as:
    • 3 or more Gout flares within the past 18 months or
    • Presence of 1 or more tophus (uric acid crystal build up around your joints) or
    • Current diagnosis of Gouty arthritis
  • 2
    Have no prior use of any uricase drugs (uricase drugs work to lower uric acid levels in the bloodstream (e.g., pegloticase [Krystexxa®], pegadricase [SEL-037], rasburicase [Elitek, Fasturtec]).
  • 3
    Are between the ages of 21 and 80.

All study-related care will be provided by a team of medical professionals.

Volunteers who take part in the study may be eligible to receive compensation for their time and travel.
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About Gout

Gout is an intermittent inflammatory arthritis characterized by elevated uric acid levels and caused by the formation of urate crystals in joint fluid leading to intensely painful joint inflammation.

Most symptoms present as intermittent attacks or flares while others present as more severe, chronic disease affecting one or more joints and may include:

  • Intense joint pain.
  • Redness, inflammation and tenderness.
  • Limited motion with a warm sensation.
  • Discomfort that can last from a few days or up to a week.

Gout is a form of inflammatory arthritis that develops when urate crystals build up in a person's joint, causing sudden severe episodes of pain, tenderness, redness warmth and swelling. These urate crystals form when the body has a high level of uric acid. Because urates are a bi-product of purines (a substance found naturally in the body), certain foods and health conditions may put certain people at risk. If too much uric acid is produced, a sharp, needle-like urate crystal could develop in a joint or surrounding tissue, in turn causing the pain and inflammation.

Factors that increase the uric acid level in your body (the cause of Gout) include:

  • Diet. Eating a diet that involves a large consumption of meat, seafood, and heavily sweetened beverages may also put people at risk. Alcoholic beverages are especially known for being a risk factor.
  • Obesity. If you are overweight, your body will produce more uric acid.
  • Medical conditions. Certain conditions can increase your risk of Gout. These include high blood pressure, diabetes, metabolic syndrome, and heart and kidney diseases.
  • Certain medications. There is a link between hypertension treatments and high uric acid levels.
  • Family history and age/sex. It primarily occurs in males between the ages of 30 and 50, while women develop signs and symptoms after menopause.

Frequently Asked Questions

What can you expect from the Gout Studies?

The Gout studies are expected to include approximately 150 patients in the USA.

Your participation in a study may last up to 8 and a half months and will include visits to a study clinic in your location. At these visits you will be given the study medications and undergo various assessments to evaluate your health. As the first step, you will be invited to visit a nearby study clinic where you will be given details about the study and complete any preliminary screening tests.

All study-related care is provided at no cost to you. You do not need health insurance to participate.

Volunteers who take part in the study will be compensated for their time and travel in the study.

A Clinical research study, or a clinical trial, is a medical study that helps to answer important questions about an investigational drug or device. For example, is the drug or device effective? How does it compare with other drugs or devices?

All medications must be tested in clinical research studies before they can be approved by regulatory authorities for doctors to prescribe to patients. Without people taking part in these studies, we would have no new treatments. The volunteers who participate in clinical research studies play a major role in helping to advance medicine.

There is no cost to participate in the Gout Studies. If you qualify, the investigational drug, study-related tests, assessments, and visits will be provided to you at no cost. You will receive study-related care throughout the study from a team of doctors and nurses.

Volunteers who take part in the study will be compensated for their time and travel in the study.
Please discuss this with the study team when they contact you.

Sign Up

What happens if I Sign Up? If you sign up, we will match you to a study clinic in your area that is seeking participants or notify you if one becomes available. They will contact you to explain more about the study before you make your decision about participating. You will attend an in-person visit where the study team will help determine if you qualify and if the study is right for you.


If you think you might like to participate in the Gout Studies or would like more information, please enter your information below so we can see if you may qualify and can contact you about the study. Keep in mind that participation is entirely voluntary. Even if you do decide to take part in this study, you may change your mind about participating at any time.